JACoW is a publisher in Geneva, Switzerland that publishes the proceedings of accelerator conferences held around the world by an international collaboration of editors.
@inproceedings{kutsaev:linac2022-mopori09, author = {S.V. Kutsaev and R.B. Agustsson and S. Boucher and K. Kaneta and A.R. Li and K. Sheng and A.Yu. Smirnov and V.S. Yu}, % author = {S.V. Kutsaev and R.B. Agustsson and S. Boucher and K. Kaneta and A.R. Li and K. Sheng and others}, % author = {S.V. Kutsaev and others}, title = {{Linear Accelerator for Demonstration of X-Ray Radiotherapy with Flash Effect}}, booktitle = {Proc. LINAC'22}, % booktitle = {Proc. 31st International Linear Accelerator Conference (LINAC'22)}, pages = {243--246}, eid = {MOPORI09}, language = {english}, keywords = {linac, electron, solenoid, radiation, target}, venue = {Liverpool, UK}, series = {International Linear Accelerator Conference}, number = {31}, publisher = {JACoW Publishing, Geneva, Switzerland}, month = {09}, year = {2022}, issn = {2226-0366}, isbn = {978-3-95450-215-8}, doi = {10.18429/JACoW-LINAC2022-MOPORI09}, url = {https://jacow.org/linac2022/papers/mopori09.pdf}, abstract = {{Emerging evidence indicates that the therapeutic window of radiotherapy can be significantly increased using ultra-high dose rate dose delivery (FLASH), by which the normal tissue injury is reduced without compromising tumor cell killing. The dose rate required for FLASH is 40 Gy/s or higher, 2-3 orders of magnitude greater than conventional radiotherapy. Among the major technical challenges in achieving the FLASH dose rate with X-rays is a linear accelerator that is capable of producing such a high dose rate. We will discuss the design of a high dose rate 18 MeV linac capable of delivering 100 Gy/s of collimated X-rays at 20 cm. This linac is being developed by a RadiaBeam/UCLA collaboration for a preclinical system as a demonstration of the FLASH effect in small animals.}}, }