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RIS citation export for MOOPA01: Linear Accelerator for Demonstration of X-Ray Radiotherapy with Flash Effect

TY  - CONF
AU  - Kutsaev, S.V.
AU  - Agustsson, R.B.
AU  - Boucher, S.
AU  - Kaneta, K.
AU  - Li, A.R.
AU  - Sheng, K.
AU  - Smirnov, A.Yu.
AU  - Yu, V.S.
ED  - McIntosh, Peter
ED  - Burt, Graeme
ED  - Apsimon, Robert
ED  - Schaa, Volker R.W.
TI  - Linear Accelerator for Demonstration of X-Ray Radiotherapy with Flash Effect
J2  - Proc. of LINAC2022, Liverpool, UK, 28 August-02 September 2022
CY  - Liverpool, UK
T2  - International Linear Accelerator Conference
T3  - 31
LA  - english
AB  - Emerging evidence indicates that the therapeutic window of radiotherapy can be significantly increased using ultra-high dose rate dose delivery (FLASH), by which the normal tissue injury is reduced without compromising tumor cell killing. The dose rate required for FLASH is 40 Gy/s or higher, 2-3 orders of magnitude greater than conventional radiotherapy. Among the major technical challenges in achieving the FLASH dose rate with X-rays is a linear accelerator that is capable of producing such a high dose rate. We will discuss the design of a high dose rate 18 MeV linac capable of delivering 100 Gy/s of collimated X-rays at 20 cm. This linac is being developed by a RadiaBeam/UCLA collaboration for a preclinical system as a demonstration of the FLASH effect in small animals.
PB  - JACoW Publishing
CP  - Geneva, Switzerland
SP  - 243
EP  - 246
DA  - 2022/09
PY  - 2022
SN  - 2226-0366
SN  - 978-3-95450-215-8
DO  - doi:10.18429/JACoW-LINAC2022-MOPORI09
UR  - https://jacow.org/linac2022/papers/mopori09.pdf
ER  -